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To achieve these goals, clinicians should be familiar with several of theavailable guidance techniques, as each has inherent advantages and disadvantages. Duringa mean follow-up period of 24 months, the incidence of primaryend-point in the pravastatin group was 26.3% and that of in theatorvastatin group, 22.4%. This study demonstrated that lymphodepletion by both non-myeloablative agents andTBI actually increased the numbers of recipient Tregs and these cells were actively involvedin the inhibition of the anti-tumor effects of ACT (Baba 2012).

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